I have been able to get most of the Shuttle payloads to work in a 2016 Atlantis. The big issue is the locations of attachments. I used attachment manager to adjust the attachment point. I had to add some new points also. The ones using Plyon I have been able to load/work
I can not load any scenario with attached vessels, if i delete the "attachement line" entry manually in the scenario by text editor, then i can load the scenario in orbiter. The same problem has
UniversalCargoDeck4, my most important addon ever


. You can use it in Orbiter2016, but when you want to leave/save the scenario, you have to remove the core-vessel from UniversalCargoDeck, else you will get a CTD when you try to reload the scenario. This problem have not the payload-vessels. So my nice Skylon-UCD-addon and DeltagliderEX-
UCD4-PowerHover-addon are although not working normally in Orbiter2016:
https://www.orbithangar.com/searchid.php?ID=4986
https://www.orbithangar.com/searchid.php?ID=4919
You have to load it in Orbiter2010, remove all Core-Vessels from UCD4 and remove attachment of the PowerHover from DGex, save, load Orbiter 2016 and manually attach it "temporaly" for instand using. Don't forget alltimes to remove attachments/core-vessels before leaving/save the scenario. But thats not a good way for the future. Orbiter2016 seems to have big problems with attachments. But interesting, that you can use "Pylon I" attachment point, we have to find out, what here is more compatible.