We need to approach this like Professor Moriarity did in the Star Trek TNG episode where he, after discovering that he existed only as a simulation in the holodeck, decided to "escape" by tricking the crew into thinking he had done just that, when actually they were in a sim inside a sim with him.
We need to be able to identify the "real" people walking among us, the ones who are aren't simulations, but actual people enjoying this holodeck we all live in.
Then we need to prank and troll them, hard.
Of course, the solution for that is that they just pull the plug and reboot us all, but it'd be worth it just for the looks on their highly evolved faces.