It's not fresh ingredients that's artificial. But cereal grains - flour, rice, pasta etc - certainly are. We've only been using them for about as long as we've had organised agriculture, which is 10 000 years (give or take). For the majority of the history of our species, that hasn't been the case. If you want to base your diet on what we've evolved to survive on, you aren't looking back far enough.
Just to remember: I said that one doesn't really have to read lots of ingredient lists and that about 90% of what you find in a supermarket is not really necessary. Buy fruits, vegetables, spices, flour, pasta etc. and cook your own food instead to buy prepared foods.
Wheat flour consists of wheat. The pasta I buy solely consists of durum wheat semolina, i.e. wheat. There is no ingredient list required. Especially not for fruits, vegetables and spices.
Whereas prepared foods, packet soup, packet sauce, canned food etc. just all the industrial crap from the supermarket contains a lot of artificial substances (made in laboratories) and requires studying the ingredient list if you want to know what your are going to eat. It mostly consists of artificial flavours, flavour enhancer, water, fat, sugar and salt which leads you to believe that you are eating what is shown on the food package.
That flour, rice and pasta is "artificial" in a way because it's not the raw plant, is no excuse for all the artificial substances you'll find in food from the supermarket. But nice try though

---------- Post added at 05:13 AM ---------- Previous post was at 04:42 AM ----------
"Artificial" should not be used as a synonym for "unhealthy" or "fatty".
And neither for healthy as well. Whether is becomes healthy or unhealthy depends on how much and how often you eat a certain kind of food. Although there are certainly higher and lower risks for widespread diseases and cancer etc. for food that contains artificial substances.
I personally chose to not buy food that contains artificial substances, i.e. coming from a laboratory. I'm tired to research abbreviations and certain kinds of substance which you don't actually know only by reading an ingredient list. I cook my own food instead.