It could be possible, but I doubt it. Which autopilot, what vessel, and how does it break?
And are you using Orbiter 2016 or anything else?
Could you run a scenario where the fault appears, and immediately after closing Orbiter (without running a new scenario!) copy-paste the contents of the file Orbiter.log here?
Preferably inside [ CODE ] and [ /CODE ] tags (without the spaces), to make formatting better.